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KMID : 1188320140080030292
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Gut and Liver
2014 Volume.8 No. 3 p.292 ~ p.297
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Clinically Useful Diagnostic Tool of Contrast Enhanced Ultrasonography for Focal Liver Masses: Comparison to Computed Tomography and Magnetic Resonance Imaging
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Ryu Sung-Woo
Bok Gene-Hyun
Jang Jae-Young
Jeong Soung-Won
Ham Nam-Seok
Kim Ji-Hye
Park Eui-Ju
Kim Jin-Nyoung
Lee Woong-Cheul
Shim Kwang-Yeun
Lee Sae-Hwan
Kim Sang-Gyune
Cha Sang-Woo
Kim Young-Seok
Cho Young-Deok
Kim Hong-Soo
Kim Boo-Sung
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Abstract
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Background/Aims:To evaluate the diagnostic value of contrast (SonoVue®) enhancement ultrasonography (CEUS) and to compare this method with computed tomography (CT) and magnetic resonance imaging (MRI) in evaluating liver masses.
Methods:CEUS (n=50), CT (n=47), and MRI (n=43) were performed on 50 liver masses in 48 patients for baseline mass characterization. The most likely impression for each modality and the final diagnosis, based on the combined biopsy results (n=14), angiography findings (n=36), and clinical course, were determined. The diagnostic value of CEUS was compared to those of CT and MRI.
Results:The final diagnosis of the masses was hepatocellular carcinoma (n=43), hemangioma (n=3), benign adenoma (n=2), eosinophilic abscess (n=1), and liver metastasis (n=1). The overall diagnostic agreement with the final diagnosis was substantial for CEUS, CT, and MRI, with κ values of 0.621, 0.763, and 0.784, respectively. The sensitivity, specificity, and accuracy were 83.3%, 87.5%, and 84.0%, respectively, for CEUS; 95.0%, 87.5%, and 93.8%, respectively, for CT; and 94.6%, 83.3%, and 93.0%, respectively for MRI. After excluding the lesions with poor acoustic sonographic windows, the sensitivity, specificity, and accuracy for CEUS were 94.6%, 87.5%, and 93.3%, respectively, with a κ value of 0.765.
Conclusions:If an appropriate acoustic window is available, CEUS is comparable to CT and MRI for the diagnosis of liver masses.
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KEYWORD
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Contrast enhanced ultrasonography, Liver masses
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